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Filtered Search Results
ABclonal Technology TAP2 Rabbit mAb
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The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters ABC proteins transport various molecules across extra- and intra-cellular membranes ABC genes are divided into seven distinct subfamilies (ABC1 MDR TAP MRP ALD OABP GCN20 White) This protein is a member of the MDR TAP subfamily Members of the MDR TAP subfamily are involved in multidrug resistance This gene is located 7 kb telomeric to gene family member ABCB2 The protein encoded by this gene is involved in antigen presentation This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum Mutations in this gene may be associated with ankylosing spondylitis insulin-dependent diabetes mellitus and celiac disease Alternative splicing of this gene produces products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules
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ABclonal Technology OTC Rabbit mAb
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This nuclear gene encodes a mitochondrial matrix enzyme The encoded protein is involved in the urea cycle which functions to detoxify ammonia into urea for excretion Mutations in this enzyme lead to ornithine transcarbamylase deficiency which causes hyperammonemia
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ABclonal Technology AUH Rabbit mAb
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This gene encodes bifunctional mitochondrial protein that has both RNA-binding and hydratase activities The encoded protein is a methylglutaconyl-CoA hydratase that catalyzes the hydration of 3-methylglutaconyl-CoA to 3-hydroxy-3-methyl-glutaryl-CoA a critical step in the leucine degradation pathway This protein also binds AU-rich elements (AREs) found in the 3 UTRs of rapidly decaying mRNAs including c-fos c-myc and granulocyte macrophage colony stimulating factor ARE elements are involved in directing RNA to rapid degradation and deadenylation This protein is localizes to the mitochondrial matrix and the inner mitochondrial membrane and may be involved in mitochondrial protein synthesis Mutations in this gene are the cause of 3-methylglutaconic aciduria type I Alternative splicing results in multiple transcript variants
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Cayman Chemical MusashI2 RabbIt MoncLNal A
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A cucurbitane glycoside
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ABclonal Technology 647 Rabbit anti- CD205/DEC-205
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Predicted to enable signaling receptor activity Predicted to act upstream of or within endocytosis Located in external side of plasma membrane Is expressed in thymus and thymus primordium Orthologous to several human genes including LY75-CD302 (LY75-CD302 readthrough)
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ABclonal Technology Villin1 Rabbit mAb
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This gene encodes a member of a family of calcium-regulated actin-binding proteins This protein represents a dominant part of the brush border cytoskeleton which functions in the capping severing and bundling of actin filaments Two mRNAs of 2 7 kb and 3 5 kb have been observed they result from utilization of alternate poly-adenylation signals present in the terminal exon
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ABclonal Technology Puromycin Rabbit mAb
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Puromycin is an aminonucleoside antibiotic derived from the Streptomyces alboniger bacterium that causes premature chain termination during translation taking place in the ribosome It has a role as a nucleoside antibiotic an antiinfective agent an antineoplastic agent a protein synthesis inhibitor an antimicrobial agent an EC 3 4 11 14 (cytosol alanyl aminopeptidase) inhibitor and an EC 3 4 14 2 (dipeptidyl-peptidase II) inhibitor It is a conjugate base of a puromycin(1 ) Puromycin is an antibiotic that prevents bacterial protein translation It is utilized as a selective agent in laboratory cell cultures Puromycin is toxic to both prokaryotic and eukaryotic cells resulting in significant cell death at appropriate doses
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ABclonal Technology eIF1A Rabbit mAb
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This gene encodes an essential eukaryotic translation initiation factor The protein is required for the binding of the 43S complex (a 40S subunit eIF2 GTP Met-tRNAi and eIF3) to the 5 end of capped RNA
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ABclonal Technology BTN2A1 Rabbit mAb
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This gene encodes a member of the immunoglobulin superfamily The gene is located in a cluster of butyrophilin-like genes in the juxta-telomeric region of the major histocompatibility complex on chromosome 6 A pseudogene of this gene has been identified in this cluster The encoded protein is an integral plasma membrane protein involved in lipid fatty-acid and sterol metabolism Alterations in this gene may be associated with several disease states including metabolic syndrome Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene
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Genscript Corporation MonoRab Rabbit Anti-scFv Cock
This product is specific for scFvs in various species (humanized mouse) various orders (VH-linker-VL VL-linker-VH) and various forms of scFv-based bispecific antibodies(DART BiTE TandAbs IgG(H)-scFv2 scFv-Fab-Fc etc) This product exhibits minimal cross-reactivity with human mouse goat and rabbit immunoglobulins
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ABclonal Technology MFI2 Rabbit mAb
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The protein encoded by this gene is a cell-surface glycoprotein found on melanoma cells The protein shares sequence similarity and iron-binding properties with members of the transferrin superfamily The importance of the iron binding function has not yet been identified This gene resides in the same region of chromosome 3 as members of the transferrin superfamily Alternative splicing results in two transcript variants
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United States Biological Corporation ANTI-C1QTNF1 NT RABBIT POLY AN
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NC3728128 ANTI-C1QTNF1 NT RABBIT POLY AN
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ABclonal Technology NDUFV1 Rabbit mAb
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The mitochondrial respiratory chain provides energy to cells via oxidative phosphorylation and consists of four membrane-bound electron-transporting protein complexes (I-IV) and an ATP synthase (complex V) This gene encodes a 51 kDa subunit of the NADH ubiquinone oxidoreductase complex I a large complex with at least 45 nuclear and mitochondrial encoded subunits that liberates electrons from NADH and channels them to ubiquinone This subunit carries the NADH-binding site as well as flavin mononucleotide (FMN)- and Fe-S-biding sites Defects in complex I are a common cause of mitochondrial dysfunction a syndrome that occurs in approximately 1 in 10 000 live births Mitochondrial complex I deficiency is linked to myopathies encephalomyopathies and neurodegenerative disorders such as Parkinson s disease and Leigh syndrome Alternative splicing results in multiple transcript variants encoding distinct isoforms
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American Research Products Inc Rabbit MatriX Metalloproteinas
Rabbit MatriX Metalloproteinase 13 MMP-13 ELISA Kit from CUSABIO Detection Range 93 75 pg/mL-6000 pg/mL Sensitivity 23 44 pg/mL Sample serum plasma tissue homogenates Method Sandwich
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Cayman Chemical CR2CD21C-Term RabbIt Mon 100uL
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An adenosine A2A and A2B receptor dual antagonist inhibits the ability of adenosine to suppress activation of human CD4 or CD8 T cells as well as monocyte-derived dendritic cells in vitro reduces tumor growth in an AT3-OVA syngeneic mouse model alone or in combination with doxorubicin acts synergistically with an anti-PD-1 antibody to reduce tumor growth in a B16/F10 syngeneic mouse model
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